11-Deoxycortisol
Alternate test name
Specific Compound S, Rechstein's Substance S, Cortodoxone, Cortexolone
Lab area
Clinical Biochemistry - Special
Method and equipment
LC-MS/MS
Expected turn-around time
14 days
Specimen type
500 uL Serum or Plasma
Specimen requirements
- Collect 1mL whole blood, spin, separate and freeze (-20oC)
- Specimens collected on an SST tube should be separated within 90 minutes of receipt.
- Avoid repeated freeze-thaw cycles.
Storage and transportation
Frozen
Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
Canada
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Background and clinical significance
11-Deoxycortisol (Compound S) is useful in diagnosing patients with 11-beta-hydroxylase deficiency (second leading cause of congenital adrenal hyperplasia) and primary (adrenal failure) or secondary (hypothalamic-pituitary ACTH deficiency) adrenal insufficiency.
Please Note: Androstenedione,17 OH Progesterone, Testosterone by LC-MS/MS, Progesterone, 21 OH Progesterone, Corticosterone, Cortisol by LC-MS/MS and 11-Deoxycortisol are all tested together as part of a panel.
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Customer Service
Toll Free: 1-855-381-3212
Local: 416-813-7200