Broad Spectrum Drug Screen, serum

Alternate test name

Blood Drug Screen

Lab area

Clinical Biochemistry - TDM & Toxicology

Method and equipment

LC-MS/MS

Expected turn-around time

Stat: 3 hours Routine: 24 hrs

Specimen type

Serum

Specimen requirements

2.0 mL

Storage and transportation

Stability

4°C - 3 days (transport with a cool pack if possible)

Room temperature - 6 hours

Shipping information

The Hospital for Sick Children

Rapid Response Laboratory

555 University Avenue, Room 3642

Toronto, ON

Canada

M5G 1X8

Phone: 416-813-7200

Toll Free: 1-855-381-3212

Hours: 7 days/week, 24 hours/day

Background and clinical significance

Screen and confirmation for a wide variety of individual drugs by LC-MS/MS (Liquid chromatography - Mass spectrometry/ Mass spectrometry). Currently there are over 400 drugs in the Broad Spectrum Drug Library (Parent & Metabolites)

Includes many of the drug classes normally done by immunoassay: Amphetamine/Methamphetamine, Cocaine metabolite, Ecstasy, Methadone/Methadone metabolite, Opiates, Oxycodone, PCP, Tricyclics. (Note: Cannabinoid metabolites and Barbiturates are not included in this test and must be ordered separately).

Reported as "Detected" based on a minimum concentration of drug being present to allow for proper identification of the drug by matching the MS (Mass spectrometry) spectra of the unknown compound to the Mass Spectrometry Spectra in the library. Phone the Toxicology Laboratory at 416-813-5906, to check on the availability of any specific drug if not listed here.

Complete Drug Screen Compound List

Please see a list of detectable compounds from the list below (or the link attached):

Compound Name	Drug Class	Trade Names (not exhaustive)	Comments
AB-Fubinaca	Psychoactive		Cannabinoid receptor agonist
Acetaminophen	NSAID	Tylenol	Paracetamol
Acetyl Fentanil	Opioid		Analog of Fentanyl
Acetyl Norfentanil	Opioid		Analog of Fentanyl
Aciclovir	Antiviral	ZOVIRAX
Alfentanil	Opioid	Alfenta, Rapifen
alpha-Hydroxyalprazolam	Benzodiazepine	Xanax	Metabolite of Alprazolam and Adinazolam
alpha-Hydroxymetoprolol	Anti-hypertensive	Lopressor, Toprol XL	Metabolite of Metoprolol
alpha-Hydroxymidazolam	Benzodiazepine	Dormicum, Hypnovel	Metabolite of Midazolam
alpha-Hydroxytriazolam	Benzodiazepine
Alprazolam	Benzodiazepine	Xanax
AM2201	Synthetic cannabinoid receptor agonist
AM2201 4-OH-Pentyl Metabolite	Psychoactive		Metabolite of AM2201
AM2233	Synthetic cannabinoid receptor agonist
Amantadine	Antidyskinetic	Gocovri
Amiloride	Diuretic	Midamor
Amiodarone	Anti-arrythmic	Cordarone, Pacerone
Amitriptyline	Tricyclic antidepressant	Elavil, Vanatrip
Amlodipine	Antihypertensive	Norvasc
Amoxapine	Tricyclic antidepressant	Asendin
Amphetamine	Stimulant	Adderall, Concerta, Ritalin, Vyvanse
Apomorphine	Dopamine agonist, anti-parkinsonian drug	Apokyn
Aripiprazole	Antipsychotic	Abilify, Aristada
Aripiprazole OPC Met	Antipsychotic	Abilify, Aristada
Atenolol	Antihypertensive	Tenormin
Atomoxetine¹	Psychostimulant	Strattera
Atorvastatin	Lipid reducing agent	Lipitor
Atropine	Anticholinergic	AtroPen
Baclofen	Anti-spastic	Lioresal
Benztropine	Anticholinergic	Cogentin
Benzocaine	Local anesthetic	Anbesol, Lanacane, Orajel
Benzoylecgonine	Cocaine	Esterom	Metabolite of Cocaine
Benzoylecgonine Isopropyl Ester	Cocaine		Metabolite of Cocaine
Benzoylecgonine Propyl Ester	Cocaine		Metabolite of Cocaine
Benzphetamine	Stimulant	Didrex	Substituted Amphetamine
Benzthiazide	Diuretic	Aquatag, Dihydrex, Diucen, Edemax, Exna, Foven
Benzylpencicillin^1,2	Antibiotic	Pfizerpen	Amphetamine
Benzylpiperazine	Stimulant
Bisoprolol	Antihypertensive	Monocor, Zebeta
Bromazepam	Benzodiazepine	Lectopam, Lexotan, Lexilium, Lexaurin, Brazepam, Rekotnil, Lexotanil
Bromo DragonFly	Serotonin receptor agonist
Brompheniramine	Antihistamine	Dimetapp
Bumetanide	Diuretic	Bumex
Buphedrone	Antihypertensive	Akovaz, Corphedra
Bupivacaine	Anti-anesthetic	Marcaine
Buprenorphine¹	Opioid	Subutex
Buprenorphine-3-beta-Glucuronide	Opioid	Subutex	Metabolite of Buprenorphine
Bupropion	Antidepressant	Wellbutrin
Bupropion OH Metabolite	Antidepressant	Wellbutrin	Metabolite of Bupropion
Buspirone	Anti-anxiety	Buspar
Butorphanol	Opioid	Stadol, Torbutrol, Torbugesic, Dolorex
Butylone	Psychoactive
Canrenone	Diuretic	Contaren, Luvion, Phanurane, and Spiroletan
Carbamazepine	Anti-epileptic	Tegretol, Curatil
Carbamazepine 10-11-Epoxide	Anti-epileptic	Tegretol, Curatil	Metabolite of Carbamazepine
Carfentanil	Sedative	Widnil
Carvedilol	Antihypertensive	Coreg
Cetirizine	Antihistamine	Allacan, Benadryl Allergy, Piriteze Allergy, Zirtek Allergy
Chlordiazepoxide	Benzodiazepine	Librium
Chlorpheniramine	Antihistamine	ChlorTrimeton, Chlor-Tripolon, Histalon
Chlorpromazine	Antipsychotic	Thorazine, Largactil
Cimetidine	Antihistamine	Tagamet HB
Ciprofloxacin	Antibiotic	Ciproxin, Ciloxan, Cetraxal
Citalopram	Antidepressant	Celexa, Lexapro
Clenbuterol	Bronchodilator	Dilaterol, Spiropent, Ventipulmin
Clobazam	Benzodiazepine	Onfi, Sympazan
Clomipramine	Tricyclic antidepressant	Anafranil
Clonazepam	Benzodiazepine	Klonopin, Rivotril
Clonidine	Antihypertensive	Catapres
Clozapine	Antipsychotics	Clozaril
Clozapine N-Oxide	Antipsychotics	Clozaril	Metabolite of Clozapine
Cocaethylene	Cocaine		Product formed from Cocaine and Ethanol
Cocaine	Cocaine
Codeine	Opioid	Panadeine, Nurofen Plus, Mersyndol
Codeine-6-beta-D-Glucuronide	Opioid		Metabolite of Codeine
Coumarin	Appetite suppressing agent
Coumatetralyl	Antidote of anticoagulant
CP-47497^1,2	Synthetic Cannabinoid
CP-47497 C8 Homologue^1,2	Synthetic Cannabinoid
Cyclobenzaprine	Muscle relaxant	Flexeril, Amrix
Dehydroaripiprazole	Antipsychotics		Metabolite of aripiprazole
Demoxepam	Benzodiazepine		Metabolite of chlordiazepoxide
Desalkylflurazepam	Benzodiazepine		Metabolite of flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, ethyl loflazepate
Desethylamiodarone	Anti-arrhythmic		Metabolite of amiodarone
Desipramine	Tricyclic antidepressant	Norpramin
Desmethyl Cyclobenzaprine	Anti-spastic	Flexeril, Amrix	Metabolite of cyclobenzaprine
Desmethyldoxepin	Tricyclic antidepressant	Sinequan	Metabolite of Doxepin
Desmethylloperimide	Antidiarrhea	Diamode, Imodium, Imodium A-D, Imogen, Imotil, Imperim, Kaodene A-D, Kao-Paverin Caps	Metabolite of loperamide
Desmethylmirtazapine	Antidepressant	Remeron, Remeron Soltab	Metabolite of mirtazapine
Desmethylranitidine	Antacid	Zantac	Metabolite of ranitidine
Desmethyltapentadol	Opioid	Nucynta	Metabolite of tapentadol
Desmethyltramadol	Opioid	Ultram, Ultram ER, Conzip	Metabolite of Tramadol
Desmethyltrimipramine	Tricyclic antidepressant	Surmontil	Metabolite of trimipramine
Dexamethasone	Corticosteroid	DexPak, Decadron
Dextromethorphan	Anti-tussive	Benylin DM, Bronchophan, Buckleys DM, Calmylin #1, Delsym, Koffex DM, Novahistex DM, Robitussin Lingering Cold Long-Acting Cough, Robitussin Lingering Cold Long-Acting CoughGels, Children's Robitussin Cough Long-Acting
Dextrorphan	Hallucinogen
Diazepam	Benzodiazepine	Valium
Diclofenac	NSAID	Voltaren XR, Cataflam
Digoxin^1,2	Anti-arrhythmic	Lanoxin
Dihydrocodeine	Opioid	DHC Continus, DF118 Forte
Dihydrocodeine-6-beta-D-Glucuronide	Opioid	DHC Continus, DF118 Forte	Metabolite of dihydrocodeine
Dihydromorphine	Opioid	Dilaudid
Dihydromorphine-3-beta-D-Glucuronide	Opioid	Dilaudid	Metabolite of Dihydromorphine
Diltiazem	Anti-arrhythmic	Cardizem
Diphenhydramine	Antihistamine	Benadryl
Diphenhydramine Metabolite 311	Antihistamine		Metabolite of diphenhydramine
Diphenoxylate	Antimotility agent	Lomotil
Domperidone	Antinausea	Motilium
Dorzolamide	Antihypertensive	Trusopt
Dothiepin	Antidepressant	Prothiaden
Doxapram	Respiratory stimulant	Dopram, Stimulex, Respiram
Doxepin	Tricyclic antidepressant	Sinequan, Quitaxon, Adapin, Triadapin, Aponal
Doxylamine	Antihistamine	Unisom
Duloxetine^1,2	Antidepressant	Cymbalta, Yentreve
Ecgonine ethylester	Cocaine
Ecgoninemethylester	Cocaine
Enalapril	Antihypertensive	Enalaprilat, Epaned, Vasotec, Vasotec IV
Ephedrine	CNS stimulant	Akovaz, Corphedra
Eplerenone	Diuretic	Inspra
Esmolol	Antihypertensive	Brevibloc
Estazolam	Benzodiazepine	Prosom
Etizolam	Benzodiazepine	Etizest, Etilaam, Etizex, Depas, Sedekopan, Pasaden
Famotidine	Antacid	Pepcid, Zantac
Fenfluramine	Anti-epileptic	Fintepla
Fenproporex	Anti-obesity
Fentanyl	Opioid	Actiq, Duragesic, Sublimaze
Fexofenadine	Antihistamine	Allegra ODT
Flecainide	Anti-arrhythmic	Tambocor
Fluconazole	Antifungal	Azocan, Diflucan, Canesten
Flunitrazepam	Benzodiazepine	Rohypnol
Fluoxetine²	Anti-depressant	Prozac
Fluphenazine	Antipsychotic	Prolixin, Permitil
Flurazepam	Benzodiazepine	Dalmane
Fluvoxamine	Antidepressant	Luvox
Gabapentin	Anti-epileptic	Neurontin
Galantamine	Reminyl	Razadyne
Glimepiride	Anti-diabetic	Amaryl
Glipizide	Anti-diabetic	Glucotrol, Glucotrol XL, Minodiab
Glyburide	Anti-diabetic	Diabeta, Glynase PresTabs
Haloperidol	Antipsychotic	Haldol, Haldol decanoate, Serenace
Heroin	Opioid	Diamorphine
Hordenine	Anti-obesity
HU-210^1,2	Synthetic Cannabinoid
Hydrocodone	Opioid	Vicodin, Lortab
Hydromorphone	Opioid	Dilaudid, Exalgo
Hydromorphone-3-beta-D-glucuronide^1,2	Opioid agonist		Primary metabolite of hydromorphone
Hydroxymethyldioxyamphetamine²	CNS stimulant		Metabolite of MDA/MDMA
Hydroxyzine	Antihistamine	Atarax, Vistaril
Ibogaine	Dissociative psychedelic
Imipramine	Tricyclic antidepressant	Tofranil
Indapamide	Antihypertensive	Natrilix, Indipam, Rawel, Tensaid, Alkapamid
Indomethacin	NSAID	Indocin, Tivorbex
Irbesartan	Antihypertensive	Avapro
JWH-015	Synthetic cannabinoid receptor agonist
JWH-018	Analgesic
JWH-018 4-Hydroxypentyl Metabolite	Synthetic cannabinoid
JWH-018 5-Hydroxypentyl Metabolite	Synthetic cannabinoid
JWH-018 5-Pentanoic Acid Metabolite^1,2	Synthetic cannabinoid
JWH-019 5-OH-Hexyl Metabolite²	Synthetic cannabinoid
JWH-019 6-OH-Hexyl Metabolite^1,2	Synthetic cannabinoid
JWH-019/JWH122	Synthetic cannabinoid
JWH-073	Synthetic cannabinoid
JWH-073 3-Hydroxybutyl Metabolite	Synthetic cannabinoid
JWH-073 4-Butanoic Acid Metabolite	Synthetic cannabinoid
JWH-073 4-hydroxybutyl Metabolite	Synthetic cannabinoid
JWH-081	Synthetic cannabinoid
JWH-200	Synthetic cannabinoid
JWH-203	Synthetic cannabinoid
JWH-210	Synthetic cannabinoid
JWH-250	Synthetic cannabinoid
JWH-250 4-OH-Pentyl Metabolite	Synthetic cannabinoid
Ketamine	General anesthetics	Ketalar
Ketoprofen	NSAID	Orudis, Actron
Ketorolac	NSAID	Acular, Acuvail, Omidria, Readysharp Anesthetics Plus Ketorolac, Sprix, Toradol, Toronova Suik
Labetalol	Alpha and beta adrenergic antagonist	Trandate
Lamotrigine	Phenylthiazine anti-epileptic	Lamictal
Levamisol	Nicotinic receptor agonist	Ergamisol	May be used as cutting agent
Levetiracetam	Anti-convulsant, pyrrolidine	Keppra, Elepsia
Lidocaine	Local anesthetic	Lidodan, Xylocaine
Lidocaine Met MEGX	Local anesthetic		Lidocaine metabolite
Lisinopril	ACE inhibitor	Prinivil, Zestril, Qbrelis
Loperamide	Anti-diarrheal	Immodium, Diarest, Diamode
Loratadine	Anti-histamine	Claritin
Lorazepam	Benzodiazepine	Ativan, Loreev
Lormetazepam	Benzodiazepine	Noctamid	Methyllorazepam
Losartan	Antihypertensive	Cozaar
Loxapine	Anti-psychotic	Adasuve, Xylac
Lurasidone	Anti-psychotic	Latuda
Lysergide	Semi-synthetic hallucinogen	LSD, lysergic acid diethylamide
Maprotiline	Tricyclic antidepressant	Maprotiline	tetracyclic antidepressant
MBDB	Entactogen of the phenethylamine	Eden, Methyl-J
MDAI	Selective serotonin releasing agent		5,6-methylenedioxy-2-aminoindane
Medazepam	Benzodiazepine	Rudotel
Melatonin	Endogenous hormone, biogenic amine	Circadin
Meloxicam	NSAID	Mobic, Anjeso, Qmiiz, Vivlodex
Melperone	Butyrophenone anti-psychotic	Buronil
Meperidine	Opioid agonist	Demerol
Mephedrone	Synthetic stimulant		4-methylmethcathinone, 4-MMC
Mepivacaine	Local anesthetic	Carbocaine
Mescaline	Phenethylamine		Mescalin, 3,4,5-trimethyoxyphenethylamine
Mesoridazine	Phenylthiazine anti-epileptic	Serentil
Metaxalone	Muscle relaxant	Skelaxin
Methadone	Synthetic opioid agonist	Dolophine, methadose
Methadone Met EDDP	Synthetic opioid agonist		Methadone metabolite
Methamphetamine	CNS stimulant, sympathomimetic agent	Desoxyn	Metamfetamine
Methotrimeprazine	Phenothiazine, anti-psychotic	Nozinan, Levoprome, Detenler, Hirnamin, Levotomin, Neurocil
Methylephedrine	Sympathomimetic amine
Methylone	Empathogen and stimulant psychoactive drug		3,4-methylenedioxy-N-methylcathinone (MDMC)
Methylphenidate	CNS stimulant	Ritalin, Ritalin SR, Concerta, Metadate ER, QuilliChew ER, Cotempla XR-ODT
Metoclopramide	Anti-emetic agent and dopamine D2 antagonist	Gimoti, Reglan
Metolazone	Thizaide-like diuretic	Zytanix, Metoz, Zaroxolyn, Mykrox
Metoprolol	Beta blocker	Kapspargo, Lopressor, Lopressor HcT, Toprol
Mianserin	Tetracyclic anti-depressant	Tolvon
Midazolam	Benzodiazepine	Buccolam, busulfex, nayzilam, seizalam
Mirtazapine	Tetracyclic anti-depressant	Remeron
Mirtazapine N-Oxide	Tetracyclic anti-depressant	Remeron	Mirtazapine metabolite
Mitragynine	Opioid		From the Kratom plant
Modafinil¹	Stimulant	Provigil
Moperone	Butyrophenone anti-psychotic	Luvatren	Discontinued
Morphine	Opioid agonist	Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
Mycophenolic Acid	Immunosuppressant	Myfortic
Nabilone^1,2	Synthetic delta-9-THC	Cesamet
Nalbuphine	Opioid agonist-antagonist	Nubain
Nalorphine	Opioid agonist-antagonist	Lethidrone, Nalline	N-allynormoprhine
Naloxone	Opioid receptor antagonist	Kloxxado, Narcan, Suboxone, Targin, Targiniq, Zimhi, Zubsolv
Naloxone N-Oxide	Opioid receptor antagonist	Kloxxado, Narcan, Suboxone, Targin, Targiniq, Zimhi, Zubsolv	Naloxone urinary metabolite
Naltrexone	Opioid receptor antagonist	Contrave, embeda, vivitrol
Naphyrone	Cathinone, Psychostimulant	NRG-1
Naproxen	NSAID	Aleve, aleve PM, aleve-D, anaprox, naprelan, naprosyn, sallus, sudafed sinus and pain, treximet, vimovo
N-Desmethyl Sildenafil	Phosphodiesterase inhibitor	Liqrev, Revatio, Viagra, Vizarsin	major metabolite of sildenafil
N-Desmethylcitalopram	SSRI	Celexa, Ctp	active metabolite of citalopram and escitalopram
N-Desmethylclobazam	Benzodiazepine	Onfi, Sympazan	clobazam metabolite
N-Desmethylclozapine	Anti-psychotic	Clozaril, Fazaclo, Versacloz	clozapine metabolite
N-Desmethylflunitrazepam	Benzodiazepine	Rohypnol	Flunitrazepam metabolite
N-Desmethylolanzapine	Anti-psychotic	Zyprexa	Olanzapine metabolite
N-Desmethylzopiclone²	nonbenzodiazepine hypnotic	Imovane	Zopiclone metabolite
Nimetazepam	Benzodiazepine	Erimin, lavol
Nitrazepam	Benzodiazepine	Mogadon
Norbuprenorphine	Partial receptor agonist	Belbuca, Brixadi, Buprenex, Buprenorphine, Butrans, Sublocade, Suboxone, Subutex, Zubsolv	Major active metabolite of buprenorphine
Norbuprenorphine Glucuronide	Partial receptor agonist	Belbuca, Brixadi, Buprenex, Buprenorphine, Butrans, Sublocade, Suboxone, Subutex, Zubsolv	Major active metabolite of buprenorphine
Norcarfentanil	Synthetic opioid	Wildnil	Metabolite of remifentanil
Norchlordiazepoxide	Benzodiazepine	Librium	Metabolite of chlordiazepoxide
Norclomiprimine	Tricyclic antidepressant	Anafranil	Metabolite of clomipramine
Norcocaethylene	Local anesthetic	Goprelto, Numbrino	Metabolite of cocaine
Norcocaine	Local anesthetic	Goprelto, Numbrino	Metabolite of cocaine
Norcodeine	Opiate analogue	Ascomp, Cheratussin, Cheratussin Dac, Codar Ar, Codar D, Codar Gf, Codeine Contin, Covan, Damylin With Codeine, Fioricet With Codeine, Histex Ac, Linctus Codeine Blanc, M-clear Wc, M-end PE, Mar-cof BP, Mar-cof Cg, Mersyndol, Ninjacof Xg, Pseudodine C, Robaxacet-8, Robaxisal, Robitussin AC, Triacin-C, Trianal C, Triatec, Triatec-30, Triatec-8, Tusnel C, Tuxarin, Tuzistra, Tylenol With Codeine	Metabolite of codeine
Nordiazepam	Benzodiazepine	Diastat, Valium, Valtoco 5 Mg Dose Kit	Metabolite of diazepam
Nordiphenhydramine	Anti-histamine	Acetadryl, Advil PM, Aleve PM, Allegra Cooling Relief Anti-itch, Banophen, Benadryl, Benadryl Itch Stopping, Benadryl-D Allergy and Sinus, Calagel, Damylin With Codeine, Dimetapp Nighttime Cold & Congestion, Diphen, Diphenhist, Diphenist, Excedrin PM Triple Action, Goody's PM, Legatrin PM, Motrin PM, Nytol, Nytol Quickgels, Percogesic Reformulated Jan 2011, Siladryl, Simply Sleep, Sleepinal, Sominex, Triaminic Night Time Cold & Cough, Tylenol PM, Unisom, Unisom Sleep, Vanamine, Wal-dryl, Wal-som (doxylamine), Zzzquil	Metabolite of diphenhydramine
Norfentanyl	Opioid	Abstral, Actiq, Duragesic, Effentora, Fentora, Instanyl, Lazanda, Sublimaze, Subsys	Metabolite of fentanyl
Norfloxacin	broad-spectrum fluoroquinolone antibiotic	Noroxin
Norfluoxetine^1,2	SSRI
Norhydrocodone	Opioid agonist	Dalmacol, Hycet, Hycodan, Hydromet, Hysingla, Lorcet, Lortab, Norco, Obredon, Reprexain, Tussicaps, Tussionex, Vicoprofen, Xodol, Zamicet, Zohydro, Zydone	Metabolite of hydrocodone
Norketamine	General anesthetics	Ketalar	Metabolite of ketamine
Normeperidine	Opioid agonist	Demerol	Metabolite of Meperidine
Normorphine	Opioid agonist	Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex	Metabolite of morphine
Nornicotine²	Nicotine
Noroxycodone	Opioid	Endocet, Endodan Reformulated May 2009, Nalocet, Oxaydo, Oxy.IR, Oxycontin, Oxyneo, Percocet, Prolate, Rivacocet, Roxicet, Roxicodone, Roxybond, Targin, Targiniq, Xolox, Xtampza	Metabolite of oxycodone
Noroxymorphone	Opioid	Endocet, Endodan Reformulated May 2009, Nalocet, Oxaydo, Oxy.IR, Oxycontin, Oxyneo, Percocet, Prolate, Rivacocet, Roxicet, Roxicodone, Roxybond, Targin, Targiniq, Xolox, Xtampza	Metabolite of oxycodone
Norpropoxyphene	Opioid	Darvocet-N, Darvon	Metabolite of dextropropoxyphene
Norpseudoephedrine	Amphetamine	Cathine
Norsertraline^1,2	SSRI	Zoloft	Metabolite of sertraline
Nortriptyline	Tricyclic antidepressant	Aventyl, Pamelor
Norverapamil	non-dihydropyridine calcium channel blocker	Calan, Isoptin, Tarka, Verelan	Metabolite of verapamil
O-Desmethylmetoclopramide	antiemetic agent and dopamine D2 antagonist	Gimoti, Reglan	Metabolite of metoclopramide
O-Desmethylquinine	Anti-malarial	Qualaquin	Metabolite of quinine
O-Desmethylvenlafaxine	antidepressant agent and SNRI	Pristiq	Metabolite of desvenlafaxine
Olanzapine	Anti-psychotic	Lybalvi, Olazax, Symbyax, Zalasta, Zypadhera, Zyprexa
Ondansetron	serotonin 5-HT3 receptor antagonist	Zofran, Zuplenz
Oxazepam	Benzodiazepine	Oxpam
Oxcarbazepine	Anti-epileptic	Oxtellar, Trileptal
Oxybutynin	anti-muscarinic agent	Ditropan, Gelnique, Kentera, Oxytrol
Oxycodone	Opioid	Endocet, Endodan Reformulated May 2009, Nalocet, Oxaydo, Oxy.IR, Oxycontin, Oxyneo, Percocet, Prolate, Rivacocet, Roxicet, Roxicodone, Roxybond, Targin, Targiniq, Xolox, Xtampza
Oxymorphone	Opioid analgesic	Opana
Pantoprazole	Proton pump inhibitor	Protonix, Somac Control, Tecta
Pantoprazole sulfide			Metabolite of pantoprazole
Pantoprazole sulfone			Metabolite of pantoprazole
Papaverine	Alkaloid	Papaverine
Paroxetine	SSRI	Paxil, Pexeva
Pentazocine	Analgesic	Pentazocine
Pentedrone	Stimulant
Pentylone	Stimulant, SNRI
Perindoprilat^1,2	ACE inhibitor	Coversyl Arginine	Metabolite of perindopril
Perphenazine	Anti-psychotic	Trilafon
Phenacetin	NSAID
Phenazepam	Benzodiazepine	Penazepam
Phencyclidine	Hallucinogen	Angel dust
Pheniramine	Anti-histamine	Naphcon A, Opcon-A, Robitussin AC, Visine-A
Phenytoin¹	Anti-convulsant	Dilantin, Phenytek
Pioglitazone	thiazolidinedione	Actoplus Met, Actos, Duetact, Incresync, Oseni, Tandemact
PMA	Amphetamine	Paramethoxyamphetamine
PMMA	Amphetamine	Paramethoxyamphetamine
Prazepam	Benzodiazepine	Centrac, Centrax, Demetrin, Lysanxia, Mono Demetrin, Pozapam, Prasepine, Prazene, Reapam and Trepidan.
Prazosin	Antihypertensive	Minipress
Prednisolone	Glucocorticoid	Millipred Dp 6 Day
Prednisone	Glucocorticoid	Deltasone, Rayos, Winpred
Pregabalin	Anti-convulsant	Lyrica
Primidone	Anti-epileptic	Mysoline
Propoxyphene	Opioid analgesic	Darvocet-N, Darvon
Propranolol	non-selective beta adrenergic antagonist	Hemangeol, Hemangiol, Inderal, Innopran
Protriptyline	Tricyclic antidepressant	Vivactil
Pseudoephedrine	alpha and beta adrenergic agonist	Advil Cold and Sinus, Alavert D, Aleve-D, Allegra-D, Aller-tec D, Allerclear, Bromfed DM, Cheratussin Dac, Clarinex-D, Claritin-D, Codar D, Covan, Entex T, Lodrane D, Mar-cof BP, Mucinex D, Nexafed, Pseudodine C, Rescon Tablets, Semprex-D, Stahist Ad Liquid, Sudafed, Sudafed Sinus & Pain, Sudogest, Triacin-C, Tusnel C, Wal Zyr D, Wal-act, Wal-itin D, Wal-phed, Zephrex-D, Zyrtec-D
Psilocin	tryptamine alkaloid, serotonergic psychedelic substance	Psilocybin	Magic mushrooms
Psilocybin^1,2	tryptamine alkaloid, serotonergic psychedelic substance	Psilocybin	Magic mushrooms
Pyrovalerone	Psychoactive, stimulant, NDRI	Centroton and Thymergix
Quetiapine	Anti-psychotic	Seroquel
Quetiapine Sulfoxide	Anti-psychotic	Seroquel	Metabolite of quetiapine
Quinine	Anti-malarial	Qualaquin
Ramelteon	CNS depressant, melatonin receptor agonist	Rozerem
Ramipril	ACE inhibitor	Altace, Altace HCT
Ramiprilat	ACE inhibitor	Altace, Altace HCT	Metabolite of ramipril
Ranitidine	histamine H2 antagonist	Good Sense Acid Reducer, Wal-zan, Zantac
RCS-4	Synthetic cannabinoid receptor agonist	SR-19, BTM-4, or Eric-4
RCS-8	Synthetic cannabinoid receptor agonist
Remifentanil	Opioid analgesic	Ultiva
Repaglinide	Anti-hyperglycemic	Enyglid, Gluconorm, Prandin
Risperidone	Anti-psychotic	Perseris, Risperdal, Rykindo, Uzedy
Ritalinic Acid	Stimulant	Adhansia, Aptensio, Biphentin, Concerta, Cotempla, Daytrana, Foquest, Jornay, Metadate, Methylin, Quillichew, Quillivant, Relexxii, Ritalin	Metabolite of methylphenidate
Rufinamide	Anti-epileptic	Banzel, Inovelon
Saquinavir	HIV protease inhibitor	Invirase
Salbutamol	beta-2 adrenergic receptor agonist	Airomir, Combivent, Proair, Proventil, Ventolin, Xopenex
Scopolamine	tropane alkaloid and anticholinergic	Donnatal, Phenohytro, Transderm Scop
Selegilin	monoamine oxidase inhibitor	Emsam, Zelapar
Sertraline	SSRI	Zoloft
Sibutramine	norepinephrine, serotonin and dopamine reuptake inhibitor	Meridia
Sildenafil	phosphodiesterase inhibitor	Liqrev, Revatio, Viagra, Vizarsin
Sotalol	methane sulfonanilide beta adrenergic antagonist	Betapace, Sorine, Sotylize
Strychnine	crystalline alkaloid	Boomer-Rid, Certox, Dog-button, Dolco mouse Ceral, Gopher Bait, Gopher Gitter, Kwik-kill, Stricnina, Mole death, Mouse-nots, Mouse-rid, Mouse-tox, Ro-dex, Strychnos, Sanaseed,
Sufentanil	Opioid	Dsuvia, Sufenta
Tapentadol	Opioid	Nucynta
Telmisartan	Antihypertensive	Micardis
Temazepam	Benzodiazepine	Restoril
Thebaine	Opioid+B363
Thioridazine¹	Phenothiazine, anti-psychotic	Thioridazine
Timolol	non-selective beta adrenergic blocker	Azarga, Betimol, Combigan, Cosopt, Duotrav, Istalol, Timoptic, Xalacom
Tocainide	class 1b antiarrhythmic	Tocainide
Tolbutamide	Sulfonylurea	Tolbutamide
Torsemide	Diuretic	Demadex, Soaanz
Tramadol	Opioid agonist, SNRI	Conzip, Durela, Qdolo, Ralivia, Ryzolt, Seglentis, Tridural, Ultracet, Ultram, Zytram
Trazodone	SSRI	Desyrel, Oleptro
Triamterene	potassium-sparing diuretic	Dyrenium, Maxzide
Triazolam	Benzodiazepine	Halcion
Trifluoromethylphenylpiperazine	Stimulant	Legal X	TFMPP
Trimethoprim	antifolate antibiotic	Bactrim, Polytrim, Primsol, Septra, Sulfatrim
Trimipramine	Tricyclic antidepressant	Surmontil
Valsartan	angiotensin-receptor blocker	Dafiro, Diovan, Diovan Hct, Entresto, Exforge, Exforge Hct
Vardenafil	phosphodiesterase 5 inhibitor	Levitra, Staxyn
Varenicline	partial agonist at nicotinic acetylcholine receptors	Champix, Chantix, Tyrvaya
Venlafaxine	SNRI	Effexor
Verapamil	non-dihydropyridine calcium channel blocker	Calan, Isoptin, Tarka, Verelan
Vilazodone	Anti-depressant	Viibryd
Voriconazole	triazole compound, anti-fungal	Vfend
Warfarin	vitamin K antagonist	Coumadin, Jantoven
XLR-11	potent agonist for the cannabinoid receptors
Yohimbine	Antihypertensive
Zaleplon	Sedative	Sonata
Ziprasidone	atypical antipsychotic	Geodon, Zeldox
Zolpidem	Sedative hypnotic	mbien, Edluar, Intermezzo, Tovalt
Zolpidem Phenyl-4-Carboxylic Acid	Non-benzodiazepine	Ambien, Stilnox®	Metabolite of zolpidem
Zopiclone²	Non-benzodiazepine hypnotics	Imovane
Zopiclone N-Oxide²	Non-benzodiazepine hypnotic	Imovan, Rhovane
Zuclopenthixol	Anti-psychotic	Clopixol
1-(3-Chlorphenyl)-Piperazine	SSRI		Trazodone metabolite
10-11-Dihydro 10-Hydroxy Carbamazepine	Antiepileptic	Tegretol, Curatil	Oxcarbazepine metabolite
10-OH Nortriptyline	Tricyclic antidepressant	Allegron, Aventyl, Noritren, Norpress, Nortrilen, Norventyl, Norzepine, Pamelor, Sensoval	Metabolite of Nortriptyline
2C-B-Fly	Phenethylamine
2-OH-Ethylflurazepam	Benzodiazepine		Metabolite of flurazepam
2-Oxo-3-OH-Lysergide	LSD		Metabolite of LSD
3-4-Methylenedioxyethylamphetamine	Amphetamine		Substituted amphetamine
3-4-Methylenedioxymethamphetamine	Amphetamine		MDMA
3-4-Methylenedioxypyrovalerone	MDPV
3-Desmethylprodine	Opioid		Analog of meperidine
3-Hydroxy Desloratadine	Antihistamine	Calrinex	Metabolite of Loratidine
3-Hydroxyquinine	Quinine	Qualaquin, Quinbisul	Metabolite of Quinine
3-Methoxymethcathinone	Methedrone		Derivative of 3-methoxymethamphetamine
4-Fluoromethcathinone	Cathinone		Flephedrone
4-Fluorotropacocaine²	Cocaine		Analog of cocaine
4-Hydroxyclonidine	Clonidine, antihypertensive	Kapvay, Nexiclon	Metabolite of Clonidine
4-Hydroxyduloxetine^1,2	Antidepressants	Cymbalta	Metabolite of duloxetine
4-Hydroxynordiazepam	Benzodiazepine		Metabolite of Nordazepam
4-Hydroxyphencyclidine	Dissociative anesthetic
4-Hydroxytriamterene	Diuretic	Dyrenium	Metabolite of triamtrene
4-Methoxyphencyclidine	Dissociative anesthetic		Derivative of phencyclidine
4-Methyl Ethyl Ephedrine	alpha and beta-adrenergic agonist	Akovaz, Bronkaid, Corphedra, Emerphed, Primatene, Rezipres	Metabolite of ephedrine
5-Hydroxybuspirone	Antipsychotic	Buspar	Metabolite of Buspirone
6-Acetylcodeine	Opioid		Morphine
6-beta-Naloxol	Opioid antagonist		Metabolite of naloxol
6-beta-Naltrexol	Opioid antagonist		Metabolite of naltrexone
6-MAM Heroine Metabolite	Opioids		Metabolite of Heroin
7-Aminoclonazepam	Benzodiazepine	Klonopin, Rivotril	Metabolite of clonazepam
7-Aminoflunitrazepam	Benzodiazepine		Metabolite of flunitrazepam
7-Aminonitrazepam	Benzodiazepine		Metabolite of nitrazepam
7-Hydroxy Fluphenazine	Benzodiazepine		Metabolite of fluphenazine
7-Hydroxy Prochlorperazine	Antipsychotic	Compazine	Metabolite of prochlorperazine
7-Hydroxyamoxapine	Tricyclic antidepressant	Asendin	Metabolite of amoxapine
7-Hydroxyquetiapine	Antipsychotic	Seroquel, Seroquel XR	Metabolite of quetiapine
9-Hydroxyrisperidone	Antipsychotic	Invega	Paliperidone

Footnotes:
¹ - Detection limit in urine exceeds 100 ng/mL for this compound.
² - Detection limit in serum exceeds 100 ng/mL for this compound.